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DUSP12 antibody

DUSP12 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6290306
  • Target See all DUSP12 Antibodies
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    Reactivity
    • 35
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 32
    • 3
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP12 antibody is un-conjugated
    Application
    • 27
    • 16
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant Protein of human DUSP12
    Isotype
    IgG
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    Discover our top product DUSP12 Primary Antibody
  • Application Notes
    WB 1:500 - 1:2000
    Comment

    Ubiquitous, highest expression in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    Alternative Name
    DUSP12 (DUSP12 Products)
    Synonyms
    DUSP12 antibody, dusp12 antibody, zgc:114069 antibody, MGC154526 antibody, DUSP1 antibody, YVH1 antibody, 1190004O14Rik antibody, AA027408 antibody, AW049275 antibody, ESTM36 antibody, LMW-DSP4 antibody, T-DSP4 antibody, VH1 antibody, mVH1 antibody, GKAP antibody, dual specificity phosphatase 12 antibody, dual specificity phosphatase 12 L homeolog antibody, Dual specificity protein phosphatase 12 antibody, dual specificity protein phosphatase 12 antibody, DUSP12 antibody, dusp12 antibody, dusp12.L antibody, GL50803_36315 antibody, MGYG_01770 antibody, Dusp12 antibody
    Background
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
    Molecular Weight
    37.687 kDa
    Gene ID
    11266
    UniProt
    Q9UNI6
    Pathways
    Regulation of Carbohydrate Metabolic Process
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