DGCR14 antibody

Catalog No. ABIN6290316

Product Details anti-DGCR14 Antibody

Target: DGCR14 (DiGeorge Syndrome Critical Region Gene 14 (DGCR14))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGCR14 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant Protein of human DGCR14

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highly expressed in heart, brain and skeletal muscle, Detected at low levels in placenta

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for DGCR14

Target: DGCR14 (DiGeorge Syndrome Critical Region Gene 14 (DGCR14))

Alternative Name: DGCR14 (DGCR14 Products)

Synonyms: DGCR13 antibody, DGS-H antibody, DGS-I antibody, DGSH antibody, DGSI antibody, ES2 antibody, Es2el antibody, AI462402 antibody, D16H22S1269E antibody, Dgcr1 antibody, Dgsi antibody, fc19d10 antibody, wu:fc19d10 antibody, zgc:162979 antibody, MGC82189 antibody, DGCR14 antibody, es2 antibody, dgsi antibody, dgs-h antibody, dgs-i antibody, es2el antibody, dgcr13 antibody, ess-2 splicing factor homolog antibody, DiGeorge syndrome critical region gene 14 antibody, ess-2 splicing factor homolog S homeolog antibody, ESS2 antibody, Dgcr14 antibody, ess2 antibody, Ess2 antibody, DGCR14 antibody, ess2.S antibody

Background: This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 52.568 kDa

Gene ID: 8220

UniProt: Q96DF8