RAD1 antibody

Catalog No. ABIN6290854

Product Details anti-RAD1 Antibody

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human RAD1

Isotype: IgG

Application Details

Application Notes: IHC 1:20 - 1:200
IF 1:50 - 1:200

Comment:

Expressed in testis, uterus, bladder, spleen, ovaries, lung, brain and muscle (at protein level)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for RAD1

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Alternative Name: RAD1 (RAD1 Products)

Synonyms: HRAD1 antibody, REC1 antibody, zgc:56502 antibody, zgc:77779 antibody, RAD1 antibody, xrad1 antibody, DKFZp459H1127 antibody, RAD1 checkpoint DNA exonuclease antibody, RAD1 homolog (S. pombe) antibody, RAD1 antibody, Rad1 antibody, rad1 antibody

Background: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.

Molecular Weight: 31.827 kDa

Gene ID: 5810

UniProt: O60671

Pathways: M Phase