SP110 antibody

Catalog No. ABIN6290941

Product Details anti-SP110 Antibody

Target: SP110 (SP110 Nuclear Body Protein (SP110))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SP110 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human SP110

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Comment:

Highly expressed in peripheral blood leukocytes and spleen, Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for SP110

Target: SP110 (SP110 Nuclear Body Protein (SP110))

Alternative Name: SP110 (SP110 Products)

Synonyms: SP110 antibody, IFI41 antibody, IFI75 antibody, IPR1 antibody, VODI antibody, 5031415C07Rik antibody, 52kDa antibody, 5830484A20Rik antibody, ENSMUSG00000075603 antibody, Ifi75 antibody, Ipr1 antibody, SP110 nuclear body protein antibody, Sp110 nuclear body protein antibody, SP110 antibody, Sp110 antibody

Background: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Molecular Weight: 78.396 kDa

Gene ID: 3431

UniProt: Q9HB58