WISP3 antibody

Catalog No. ABIN6291067

Product Details anti-WISP3 Antibody

Target: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WISP3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human WISP3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Predominant expression in adult kidney and testis and fetal kidney, Weaker expression found in placenta, ovary, prostate and small intestine, Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for WISP3

Target: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Alternative Name: WISP3 (WISP3 Products)

Synonyms: CCN6 antibody, LIBC antibody, PPAC antibody, PPD antibody, ENSMUSG00000062074 antibody, Gm735 antibody, WISP-3 antibody, RGD1564120 antibody, WISP3 antibody, si:dkey-119m7.6 antibody, WNT1 inducible signaling pathway protein 3 antibody, WISP3 antibody, Wisp3 antibody, wisp3 antibody

Background: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 39.293 kDa

Gene ID: 8838

UniProt: O95389

Pathways: WNT Signaling, Growth Factor Binding