CDH18 antibody

Catalog No. ABIN6291131

Product Details anti-CDH18 Antibody

Target: CDH18 (Cadherin 18, Type 2 (CDH18))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDH18 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human CDH18

Isotype: IgG

Application Details

Application Notes: IHC 1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CDH18

Target: CDH18 (Cadherin 18, Type 2 (CDH18))

Alternative Name: CDH18 (CDH18 Products)

Synonyms: B230220E17Rik antibody, Cdh14l antibody, CDH14 antibody, CDH14L antibody, CDH24 antibody, cadherin 18 antibody, Cdh18 antibody, CDH18 antibody

Background: This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 88.073 kDa

Gene ID: 1016

UniProt: Q13634

Pathways: Cell-Cell Junction Organization