TPBG antibody

Catalog No. ABIN6291221

Product Details anti-TPBG Antibody

Target: TPBG (Trophoblast Glycoprotein (TPBG))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPBG antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human TPBG

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed by all types of trophoblasts as early as 9 weeks of development, Specific for trophoblastic cells except for amniotic epithelium, In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for TPBG

Target: TPBG (Trophoblast Glycoprotein (TPBG))

Alternative Name: TPBG (TPBG Products)

Synonyms: 5T4 antibody, 5T4AG antibody, M6P1 antibody, AW495680 antibody, TPBG antibody, tpbg antibody, trophoblast glycoprotein antibody, trophoblast glycoprotein b antibody, TPBG antibody, Tpbg antibody, tpbgb antibody, tpbg antibody

Background: This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Molecular Weight: 46.032 kDa

Gene ID: 7162

UniProt: Q13641