UNC5B antibody

Catalog No. ABIN6291227

Product Details anti-UNC5B Antibody

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human UNC5B

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highly expressed in brain, Also expressed at lower level in developing lung, cartilage, kidney and hematopoietic and immune tissues

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for UNC5B

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Alternative Name: UNC5B (UNC5B Products)

Synonyms: unc5h2 antibody, 6330415E02Rik antibody, A630020F16 antibody, D10Bwg0792e antibody, Unc5h2 antibody, UNC5H2 antibody, p53RDL1 antibody, UNC5C antibody, UNC5B antibody, p53rdl1 antibody, unc-5 netrin receptor B antibody, unc-5 netrin receptor B L homeolog antibody, unc5b antibody, Unc5b antibody, UNC5B antibody, unc5b.L antibody

Background: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

Molecular Weight: 103.638 kDa

Gene ID: 219699

UniProt: Q8IZJ1