AKAP5 antibody
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- Target See all AKAP5 Antibodies
- AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AKAP5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human AKAP5
- Isotype
- IgG
- Top Product
- Discover our top product AKAP5 Primary Antibody
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- Application Notes
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WB 1:500 - 1:2000
IF 1:50 - 1:200 - Comment
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Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))
- Alternative Name
- AKAP5 (AKAP5 Products)
- Synonyms
- AKAP5 antibody, AKAP75 antibody, AKAP79 antibody, H21 antibody, AKAP antibody, P75 antibody, 3526401B18Rik antibody, AKAP 150 antibody, AKAP-5 antibody, AKAP150 antibody, BB098886 antibody, Gm258 antibody, P150 antibody, Akap79 antibody, A kinase (PRKA) anchor protein 5 antibody, A-kinase anchoring protein 5 antibody, AKAP5 antibody, Akap5 antibody
- Target Type
- Viral Protein
- Background
- The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.
- Molecular Weight
- 47.088 kDa
- Gene ID
- 9495
- UniProt
- P24588
- Pathways
- cAMP Metabolic Process
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