JAG2 antibody

Catalog No. ABIN6291337

Product Details anti-JAG2 Antibody

Target: JAG2 (Jagged 2 (JAG2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human JAG2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed in heart, placenta and skeletal muscle and to a lesser extent in pancreas, Very low expression in brain, lung, liver and kidney

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for JAG2

Target: JAG2 (Jagged 2 (JAG2))

Alternative Name: JAG2 (JAG2 Products)

Background: The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 133.367 kDa

Gene ID: 3714

UniProt: Q9Y219

Pathways: Notch Signaling, Sensory Perception of Sound