Dopamine d2 Receptor antibody

Catalog No. ABIN6291487

Product Details anti-Dopamine d2 Receptor Antibody

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dopamine d2 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human DRD2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Alternative Name: DRD2 (DRD2 Products)

Synonyms: D2DR antibody, D2R antibody, drd2b antibody, d2r2 antibody, Drd-2 antibody, d2dr antibody, d2r antibody, drd2 antibody, drd2-B antibody, DRD2 antibody, D2 antibody, CG18741 antibody, CG7569 antibody, DAMB antibody, DDR2 antibody, DOPR2 antibody, DOPR99B antibody, Dar2 antibody, Dmel\\CG18741 antibody, DopD1 antibody, DopR99B antibody, DopRII antibody, dopamine receptor D2 antibody, dopamine receptor D2 like antibody, dopamine receptor D2 L homeolog antibody, dopamine receptor D2 S homeolog antibody, Dopamine 1-like receptor 2 antibody, DRD2 antibody, drd2l antibody, drd2 antibody, Drd2 antibody, drd2.L antibody, drd2.S antibody, Dop1R2 antibody

Background: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia, other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

Molecular Weight: 50.619 kDa

Gene ID: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity