PROCR antibody

Catalog No. ABIN6291490

Product Details anti-PROCR Antibody

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROCR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human PROCR

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Comment:

Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for PROCR

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Alternative Name: PROCR (PROCR Products)

Synonyms: PROCR antibody, CCCA antibody, CCD41 antibody, EPCR antibody, AI325044 antibody, Ccca antibody, Ccd41 antibody, Epcr antibody, protein C receptor antibody, protein C receptor, endothelial antibody, PROCR antibody, Procr antibody

Background: The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.

Molecular Weight: 26.671 kDa

Gene ID: 10544

UniProt: Q9UNN8