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FBXO32 antibody

FBXO32 Reactivity: Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6291620
  • Target See all FBXO32 Antibodies
    FBXO32 (F-Box Protein 32 (FBXO32))
    Reactivity
    • 48
    • 38
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Mouse
    Host
    • 45
    • 6
    • 1
    Rabbit
    Clonality
    • 40
    • 12
    Polyclonal
    Conjugate
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO32 antibody is un-conjugated
    Application
    • 37
    • 14
    • 14
    • 13
    • 12
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human FBXO32
    Isotype
    IgG
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  • Application Notes
    WB 1:200 - 1:500
    Comment

    Specifically expressed in cardiac and skeletal muscle

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    FBXO32 (F-Box Protein 32 (FBXO32))
    Alternative Name
    FBXO32 (FBXO32 Products)
    Synonyms
    MGC56479 antibody, zgc:56479 antibody, Fbx32 antibody, MAFbx antibody, 4833442G10Rik antibody, AI430017 antibody, ATROGIN1 antibody, Gm20361 antibody, Atrogin1 antibody, F-box protein 32 antibody, fbxo32 antibody, FBXO32 antibody, Fbxo32 antibody
    Background
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molecular Weight
    41.637 kDa
    Gene ID
    114907
    UniProt
    Q969P5
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