SMPD4 antibody

Catalog No. ABIN6291650

Product Details anti-SMPD4 Antibody

Target: SMPD4 (Sphingomyelin Phosphodiesterase 4 (SMPD4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human SMPD4

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Widely expressed, with highest levels in heart and skeletal muscle

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for SMPD4

Target: SMPD4 (Sphingomyelin Phosphodiesterase 4 (SMPD4))

Alternative Name: SMPD4 (SMPD4 Products)

Synonyms: NSMASE3 antibody, wu:fb22d05 antibody, wu:fi25e10 antibody, zgc:66367 antibody, 4122402O22Rik antibody, mKIAA1418 antibody, RGD1310674 antibody, NET13 antibody, NSMASE-3 antibody, sphingomyelin phosphodiesterase 4 antibody, sphingomyelin phosphodiesterase 4 L homeolog antibody, Sphingomyelin phosphodiesterase 4 antibody, SMPD4 antibody, smpd4.L antibody, smpd4 antibody, nsma3 antibody, Smpd4 antibody

Background: The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.

Molecular Weight: 93.352 kDa

Gene ID: 55627

UniProt: Q9NXE4