APOBEC3A antibody
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- Target See all APOBEC3A Antibodies
- APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APOBEC3A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human APOBEC3A
- Isotype
- IgG
- Top Product
- Discover our top product APOBEC3A Primary Antibody
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- Application Notes
- WB 1:200 - 1:500
- Comment
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Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells, Highly expressed in keratinocytes and in periphery blood monocytes, Also detected in non-lymphoid tissues including lung and adipose tissues, Found at high levels in colorectal adenocarcinoma, Burkitt's lymphoma and chronic myelogenous leukemia
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))
- Alternative Name
- APOBEC3A (APOBEC3A Products)
- Synonyms
- A3A antibody, ARP3 antibody, PHRBN antibody, bK150C2.1 antibody, APOBEC3A antibody, APOBEC3Z1 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3A antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1 antibody, similar to ARP10 protein antibody, APOBEC3A antibody, APOBEC3Z1 antibody
- Background
- This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 23.012 kDa
- Gene ID
- 100913187
- UniProt
- P31941
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