CCNDBP1 antibody
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- Target See all CCNDBP1 Antibodies
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCNDBP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human CCNDBP1
- Isotype
- IgG
- Top Product
- Discover our top product CCNDBP1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Comment
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Ubiquitously expressed, Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
- Alternative Name
- CCNDBP1 (CCNDBP1 Products)
- Synonyms
- CCNDBP1 antibody, dip1 antibody, gcip antibody, DIP1 antibody, GCIP antibody, HHM antibody, AU022347 antibody, Maid antibody, SECC-8 antibody, SSEC-8 antibody, cyclin D1 binding protein 1 antibody, cyclin D-type binding-protein 1 antibody, CCNDBP1 antibody, ccndbp1 antibody, Ccndbp1 antibody
- Background
- This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.
- Molecular Weight
- 40.262 kDa
- Gene ID
- 23582
- UniProt
- O95273
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