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TLR8 antibody

TLR8 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6291882
  • Target See all TLR8 Antibodies
    TLR8 (Toll-Like Receptor 8 (TLR8))
    Reactivity
    • 76
    • 41
    • 28
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 74
    • 12
    Rabbit
    Clonality
    • 74
    • 12
    Polyclonal
    Conjugate
    • 31
    • 10
    • 9
    • 9
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR8 antibody is un-conjugated
    Application
    • 67
    • 40
    • 26
    • 13
    • 13
    • 11
    • 10
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human TLR8
    Isotype
    IgG
    Top Product
    Discover our top product TLR8 Primary Antibody
  • Application Notes
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
    Comment

    Detected in brain, heart, lung, liver, placenta, in monocytes, and at lower levels in CD11c+ immature dendritic cells

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    TLR8 (Toll-Like Receptor 8 (TLR8))
    Alternative Name
    TLR8 (TLR8 Products)
    Synonyms
    CD288 antibody, toll like receptor 8 antibody, toll-like receptor 8 antibody, TLR8 antibody, Tlr8 antibody
    Background
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
    Molecular Weight
    119.828 kDa
    Gene ID
    51311
    UniProt
    Q9NR97
    Pathways
    TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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