DNAJA3 antibody

Catalog No. ABIN6292022

Product Details anti-DNAJA3 Antibody

Target: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJA3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human DNAJA3

Isotype: IgG

Application Details

Application Notes: IF 1:50 - 1:200

Comment:

Widely expressed with highest levels in heart, liver, lung and skeletal muscles, Also expressed in keratinocytes

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for DNAJA3

Target: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Alternative Name: DNAJA3 (DNAJA3 Products)

Synonyms: Tid-1 antibody, 1200003J13Rik antibody, 1810053A11Rik antibody, C81173 antibody, Tid1l antibody, HCA57 antibody, TID1 antibody, hTID-1 antibody, DnaJ heat shock protein family (Hsp40) member A3 antibody, Dnaja3 antibody, DNAJA3 antibody

Background: This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 52.489 kDa

Gene ID: 9093

UniProt: Q96EY1

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity