HNMT antibody

Catalog No. ABIN6292124

Product Details anti-HNMT Antibody

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNMT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Affinity purification

Immunogen: Recombinant protein of human HNMT

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IHC 1:50 - 1:200
IP 1:20 - 1:50

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for HNMT

Target: HNMT (Histamine N-Methyltransferase (HNMT))

Alternative Name: HNMT (HNMT Products)

Synonyms: HMT antibody, HNMT-S1 antibody, HNMT-S2 antibody, hmt antibody, hnmt antibody, hnmt-s1 antibody, hnmt-s2 antibody, zgc:100917 antibody, HNMT antibody, 1500031F01Rik antibody, AI788969 antibody, HMT A antibody, hnmt-a antibody, hnmt-b antibody, histamine N-methyltransferase antibody, histamine N-methyltransferase S homeolog antibody, histamine N-methyltransferase-like antibody, histamine N-methyltransferase L homeolog antibody, HNMT antibody, hnmt.S antibody, hnmt antibody, Hnmt antibody, LOC100228106 antibody, hnmt.L antibody

Background: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Molecular Weight: 33.295 kDa

Gene ID: 3176

UniProt: P50135