IGF2 antibody

Catalog No. ABIN6292141

Product Details anti-IGF2 Antibody

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human IGF2

Isotype: IgG

Application Details

Application Notes: IHC 1:50 - 1:200

Comment:

Expressed in heart, placenta, lung, liver, muscle, kidney, tongue, limb, eye and pancreas

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: IGF2 (IGF2 Products)

Synonyms: C11orf43 antibody, IGF-II antibody, PP9974 antibody, LOC100136550 antibody, igf2 antibody, igf2b antibody, wu:fc26e03 antibody, zgc:91781 antibody, igf-2 antibody, insigf antibody, pp9974 antibody, AL033362 antibody, Igf-2 antibody, Igf-II antibody, M6pr antibody, Mpr antibody, Peg2 antibody, IGFII antibody, RNIGF2 antibody, IGF-II-B antibody, igf2-a antibody, igf2-b antibody, insulin like growth factor 2 antibody, insulin-like growth factor II antibody, insulin-like growth factor 2a antibody, insulin like growth factor 2 S homeolog antibody, insulin-like growth factor 2 antibody, insulin-like growth factor 2 (somatomedin A) antibody, insulin like growth factor 2 L homeolog antibody, IGF2 antibody, LOC100136550 antibody, igf2a antibody, igf2.S antibody, Igf2 antibody, igf2.L antibody

Background: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 20.14 kDa

Gene ID: 3481

UniProt: P01344

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation