LEFTY2 antibody

Catalog No. ABIN6292173

Product Details anti-LEFTY2 Antibody

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEFTY2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human LEFTY2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Mesenchymal cells of the endometrial stroma

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for LEFTY2

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Alternative Name: LEFTY2 (LEFTY2 Products)

Synonyms: EBAF antibody, LEFTA antibody, LEFTYA antibody, TGFB4 antibody, AI450052 antibody, Ebaf antibody, Leftb antibody, Stra3 antibody, Tgfb4 antibody, lefty antibody, lefty-1 antibody, atv2 antibody, cb720 antibody, fe38b03 antibody, wu:fe38b03 antibody, 6030463A22Rik antibody, AV214969 antibody, Lefta antibody, Ebaf2 antibody, left-right determination factor 2 antibody, left right determination factor 1 antibody, lefty2 antibody, Left-right determination factor 2 antibody, left-right determination factor 2-like antibody, LEFTY2 antibody, Lefty1 antibody, lft2 antibody, Lefty2 antibody, LOC699676 antibody, LOC100232580 antibody

Background: This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.

Molecular Weight: 40.92 kDa

Gene ID: 7044

UniProt: O00292