TICAM1 antibody

Catalog No. ABIN6292306

Product Details anti-TICAM1 Antibody

Target: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TICAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human TICAM1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Comment:

Ubiquitously expressed but with higher levels in liver

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for TICAM1

Target: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Alternative Name: TICAM1 (TICAM1 Products)

Synonyms: IIAE6 antibody, MyD88-3 antibody, PRVTIRB antibody, TICAM-1 antibody, TRIF antibody, AW046014 antibody, AW547018 antibody, trif antibody, toll like receptor adaptor molecule 1 antibody, toll-like receptor adaptor molecule 1 antibody, TICAM1 antibody, Ticam1 antibody, ticam1 antibody

Background: This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.

Molecular Weight: 76.422 kDa

Gene ID: 148022

UniProt: Q8IUC6

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades