VPS37A antibody

Catalog No. ABIN6292343

Product Details anti-VPS37A Antibody

Target: VPS37A (Vacuolar Protein Sorting 37 Homolog A (VPS37A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS37A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human VPS37A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Comment:

Widely expressed, Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas, More abundant in liver, Strongly decreased or undetected in hepatomas

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for VPS37A

Target: VPS37A (Vacuolar Protein Sorting 37 Homolog A (VPS37A))

Alternative Name: VPS37A (VPS37A Products)

Synonyms: fb08f03 antibody, fj42c03 antibody, zgc:73244 antibody, zgc:77637 antibody, wu:fb08f03 antibody, wu:fj42c03 antibody, HCRP1 antibody, PQBP2 antibody, SPG53 antibody, 2210018P21Rik antibody, 4930592A21Rik antibody, AW261445 antibody, D8Ertd531e antibody, vacuolar protein sorting 37A antibody, VPS37A, ESCRT-I subunit antibody, vacuolar protein sorting 37 homolog A antibody, vacuolar protein sorting 37 homolog A L homeolog antibody, vps37a antibody, VPS37A antibody, vps37a.L antibody, Vps37a antibody

Background: This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 44.314 kDa

Gene ID: 137492

UniProt: Q8NEZ2