Calsyntenin 1 antibody

Catalog No. ABIN6292389

Product Details anti-Calsyntenin 1 Antibody

Target: Calsyntenin 1 (CLSTN1)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calsyntenin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CLSTN1

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Expressed in the brain and, a lower level, in the heart, skeletal muscle, kidney and placenta, Accumulates in dystrophic neurites around the amyloid core of Alzheimer disease senile plaques (at protein level)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for Calsyntenin 1

Target: Calsyntenin 1 (CLSTN1)

Alternative Name: CLSTN1 (CLSTN1 Products)

Synonyms: CALSYNTENIN-1 antibody, fm67g03 antibody, wu:fk52g02 antibody, wu:fm67g03 antibody, zgc:153744 antibody, zgc:56528 antibody, clstn1 antibody, 1810034E21Rik antibody, Cst-1 antibody, Cstn1 antibody, ALC-ALPHA antibody, CDHR12 antibody, CSTN1 antibody, PIK3CD antibody, XB31alpha antibody, alcalpha1 antibody, alcalpha2 antibody, calsyntenin 1 antibody, calsyntenin 3 antibody, beta-catenin-interacting protein 1 antibody, calsyntenin-1 antibody, CLSTN1 antibody, clstn1 antibody, clstn3 antibody, LOC100356725 antibody, LOC100435584 antibody, Clstn1 antibody, LOC479600 antibody

Background: This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Molecular Weight: 109.793 kDa

Gene ID: 22883

UniProt: O94985