DTNA antibody

Catalog No. ABIN6292450

Product Details anti-DTNA Antibody

Target: DTNA (Dystrobrevin alpha (DTNA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNA antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human DTNA

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas, Isoform 2 is not expressed in cardiac muscle, Isoform 7 and isoform 8 are only expressed in muscle

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for DTNA

Target: DTNA (Dystrobrevin alpha (DTNA))

Alternative Name: DTNA (DTNA Products)

Synonyms: adtn antibody, atnb antibody, MGC146484 antibody, 2210407P21Rik antibody, A0 antibody, Dtn antibody, a-DB-1 antibody, adbn antibody, D18S892E antibody, DRP3 antibody, DTN antibody, DTN-A antibody, LVNC1 antibody, Dtna-ps1 antibody, RGD1561985 antibody, dystrobrevin alpha antibody, dystrobrevin, alpha antibody, DTNA antibody, dtna antibody, LOC100195747 antibody, Dtna antibody

Background: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Molecular Weight: 83.901 kDa

Gene ID: 1837

UniProt: Q9Y4J8