ATP1A4 antibody

Catalog No. ABIN6292469

Product Details anti-ATP1A4 Antibody

Target: ATP1A4 (ATPase, Na+/K+ Transporting, alpha 4 Polypeptide (ATP1A4))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ATP1A4

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Specifically expressed in testis, Found in very low levels in skeletal muscle, Expressed in mature sperm (at protein level)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for ATP1A4

Target: ATP1A4 (ATPase, Na+/K+ Transporting, alpha 4 Polypeptide (ATP1A4))

Alternative Name: ATP1A4 (ATP1A4 Products)

Synonyms: ATP1A1 antibody, ATP1AL2 antibody, ATPase Na+/K+ transporting subunit alpha 4 antibody, ATPase, Na+/K+ transporting, alpha 4 polypeptide antibody, ATP1A4 antibody, Atp1a4 antibody

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 114.166 kDa

Gene ID: 480

UniProt: Q13733

Pathways: Thyroid Hormone Synthesis, Proton Transport, Ribonucleoside Biosynthetic Process