UBA3 antibody

Catalog No. ABIN6292492

Product Details anti-UBA3 Antibody

Target: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human UBA3

Isotype: IgG

Application Details

Application Notes: IF 1:50 - 1:200

Comment:

Ubiquitously expressed

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for UBA3

Target: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Alternative Name: UBA3 (UBA3 Products)

Synonyms: UBE1C antibody, hUBA3 antibody, Ube1c antibody, ube1c antibody, wu:fb75e04 antibody, wu:fc37b11 antibody, zgc:55528 antibody, A830034N06Rik antibody, AI256736 antibody, AI848246 antibody, AW546539 antibody, ubiquitin like modifier activating enzyme 3 antibody, ubiquitin-like modifier activating enzyme 3 antibody, ubiquitin like modifier activating enzyme 3 S homeolog antibody, UBA3 antibody, Uba3 antibody, uba3 antibody, uba3.S antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molecular Weight: 51.852 kDa

Gene ID: 9039

UniProt: Q8TBC4