NECAB3 antibody
-
- Target See all NECAB3 Antibodies
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This NECAB3 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human NECAB3
- Isotype
- IgG
- Top Product
- Discover our top product NECAB3 Primary Antibody
-
-
- Application Notes
- WB 1:200 - 1:2000
- Comment
-
Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
-
- Target
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
- Alternative Name
- NECAB3 (NECAB3 Products)
- Synonyms
- Apba2bp antibody, APBA2BP antibody, NECAB3 antibody, EFCBP3 antibody, NIP1 antibody, STIP3 antibody, SYTIP2 antibody, XB51 antibody, dJ63M2.4 antibody, dJ63M2.5 antibody, 2900010M17Rik antibody, AI853434 antibody, Nip1 antibody, N-terminal EF-hand calcium binding protein 3 antibody, Necab3 antibody, NECAB3 antibody
- Background
- The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 44.35 kDa
- Gene ID
- 63941
- UniProt
- Q96P71
-