CHST15 antibody

Catalog No. ABIN6292650

Product Details anti-CHST15 Antibody

Target: CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST15 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant Protein of human CHST15

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed in B-cell-enriched tissues but not in fetal or adult thymus, Expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes, Not expressed in T-cells, In pro-B, pre-B, and mature B-cell lines, it colocalizes with RAG1

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CHST15

Target: CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))

Alternative Name: CHST15 (CHST15 Products)

Synonyms: GALNAC4S-6ST antibody, BRAG antibody, RP11-47G11.1 antibody, 4631426J05Rik antibody, GalNAcS-6ST antibody, MAd5 antibody, mKIAA0598 antibody, GalNAc4S6ST antibody, Galnac4s-6st antibody, carbohydrate sulfotransferase 15 antibody, carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 antibody, CHST15 antibody, chst15 antibody, Chst15 antibody

Background: Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 64.926 kDa

Gene ID: 51363

UniProt: Q7LFX5

Pathways: Glycosaminoglycan Metabolic Process