PORCN antibody

Catalog No. ABIN6292716

Product Details anti-PORCN Antibody

Target: PORCN (Porcupine Homolog (PORCN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PORCN antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human PORCN

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Isoform 1 is expressed in fetal brain, brain, amygdala, caudate nucleus, cerebellum, hippocampus, pituitary, thalamus, heart, skeletal muscle and testis, Isoform 4 is expressed in amygdala, corpus callosum, hippocampus, spinal cord, kidney, liver, lung, spleen, uterus, testis, Isoform 2 and isoform 3 are expressed in substantia negra, spinal cord, heart and lung

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for PORCN

Target: PORCN (Porcupine Homolog (PORCN))

Alternative Name: PORCN (PORCN Products)

Synonyms: 15175 antibody, CG6205 antibody, Dmel\\CG6205 antibody, Porc antibody, dmPorc antibody, l(1)17Ac antibody, poc antibody, porc antibody, DHOF antibody, FODH antibody, MG61 antibody, PORC antibody, PPN antibody, porcupine antibody, 2410004O13Rik antibody, AW045557 antibody, DXHXS7465e antibody, Mporc antibody, Mporc-a antibody, Mporc-b antibody, Mporc-c antibody, Mporc-d antibody, Ppn antibody, mMg61 antibody, RGD1564947 antibody, porcupine antibody, porcupine O-acyltransferase antibody, porcupine homolog (Drosophila) antibody, por antibody, PORCN antibody, Porcn antibody

Background: This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molecular Weight: 52.318 kDa

Gene ID: 64840

UniProt: Q9H237