ITGA7 antibody

Catalog No. ABIN6292834

Product Details anti-ITGA7 Antibody

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA7 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ITGA7

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Isoforms containing segment A are predominantly expressed in skeletal muscle, Isoforms containing segment B are abundantly expressed in skeletal muscle, moderately in cardiac muscle, small intestine, colon, ovary and prostate and weakly in lung and testes, Isoforms containing segment X2D are expressed at low levels in fetal and adult skeletal muscle and in cardiac muscle, but are not detected in myoblasts and myotubes, In muscle fibers isoforms containing segment A and B are expressed at myotendinous and neuromuscular junctions

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for ITGA7

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Alternative Name: ITGA7 (ITGA7 Products)

Synonyms: [a]7 antibody, alpha7 antibody, integrin alpha 7 antibody, integrin subunit alpha 7 antibody, Itga7 antibody, ITGA7 antibody

Background: The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molecular Weight: 128.948 kDa

Gene ID: 3679

UniProt: Q13683

Pathways: Integrin Complex