TP53BP2 antibody

Catalog No. ABIN6292836

Product Details anti-TP53BP2 Antibody

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human TP53BP2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Widely expressed, Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte, Reduced expression in breast carcinomas expressing a wild-type TP53 protein, Overexpressed in lung cancer cell lines

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for TP53BP2

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Alternative Name: TP53BP2 (TP53BP2 Products)

Synonyms: 53BP2 antibody, ASPP2 antibody, BBP antibody, P53BP2 antibody, PPP1R13A antibody, TP53BP2 antibody, AI746547 antibody, Tp53bp2 antibody, X98550 antibody, Trp53bp2 antibody, wu:fa09h08 antibody, wu:fb04e08 antibody, zgc:85720 antibody, tumor protein p53 binding protein 2 antibody, tumor protein p53 binding protein 2 L homeolog antibody, tumor protein p53 binding protein, 2b antibody, transformation related protein 53 binding protein 2 antibody, tumor protein p53 binding protein, 2 antibody, tumor protein p53 binding protein, 2a antibody, TP53BP2 antibody, tp53bp2.L antibody, tp53bp2 antibody, tp53bp2b antibody, Trp53bp2 antibody, Tp53bp2 antibody, tp53bp2a antibody

Background: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 125.616 kDa

Gene ID: 7159

UniProt: Q13625