FCRL5 antibody

Catalog No. ABIN6292859

Product Details anti-FCRL5 Antibody

Target: FCRL5 (Fc Receptor-Like 5 (FCRL5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCRL5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human FCRL5

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil, Expressed in many lymphoma cell lines and on hairy cell leukemia cells, Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3, Expressed in mature and memory B-cells and down-regulated in germinal center cells (at protein level)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for FCRL5

Target: FCRL5 (Fc Receptor-Like 5 (FCRL5))

Alternative Name: FCRL5 (FCRL5 Products)

Synonyms: FCRL5 antibody, BXMAS1 antibody, CD307 antibody, CD307e antibody, FCRH5 antibody, IRTA2 antibody, PRO820 antibody, Fcrh3 antibody, mBXMH2 antibody, Fc receptor like 5 antibody, Fc receptor-like 5 antibody, FCRL5 antibody, Fcrl5 antibody

Background: This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 106.437 kDa

Gene ID: 83416

UniProt: Q96RD9