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KLHL3 antibody

KLHL3 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6293045
  • Target See all KLHL3 Antibodies
    KLHL3 (Kelch-Like 3 (KLHL3))
    Reactivity
    • 51
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 49
    • 2
    Rabbit
    Clonality
    • 51
    Polyclonal
    Conjugate
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLHL3 antibody is un-conjugated
    Application
    • 45
    • 24
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human KLHL3
    Isotype
    IgG
    Top Product
    Discover our top product KLHL3 Primary Antibody
  • Application Notes
    WB 1:500 - 1:2000
    Comment

    Widely expressed

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    KLHL3 (Kelch-Like 3 (KLHL3))
    Alternative Name
    KLHL3 (KLHL3 Products)
    Synonyms
    7530408C15Rik antibody, AI430941 antibody, EG627648 antibody, PHA2D antibody, RGD1565218 antibody, kelch like family member 3 antibody, kelch-like 3 antibody, kelch-like family member 3 antibody, KLHL3 antibody, Klhl3 antibody
    Background
    This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D), a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molecular Weight
    64.97 kDa
    Gene ID
    26249
    UniProt
    Q9UH77
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