RASD1 antibody

Catalog No. ABIN6293268

Product Details anti-RASD1 Antibody

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASD1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human RASD1

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Alternative Name: RASD1 (RASD1 Products)

Synonyms: AGS1 antibody, DEXRAS1 antibody, MGC:26290 antibody, Dexras1 antibody, ras related dexamethasone induced 1 antibody, RAS, dexamethasone-induced 1 antibody, RASD1 antibody, Rasd1 antibody

Background: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 31.642 kDa

Gene ID: 51655

UniProt: Q9Y272