CDY1 antibody

Catalog No. ABIN6293284

Product Details anti-CDY1 Antibody

Target: CDY1 (Chromodomain Protein, Y-Linked, 1 (CDY1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDY1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CDY1B

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Testis-specific, Detected in spermatids (at protein level)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CDY1

Target: CDY1 (Chromodomain Protein, Y-Linked, 1 (CDY1))

Alternative Name: CDY1 (CDY1 Products)

Synonyms: CDY antibody, CDY1A antibody, chromodomain Y-linked 1 antibody, CDY1 antibody

Background: This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region, this record represents the more centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.

Molecular Weight: 60.473 kDa

Gene ID: 253175

UniProt: Q9Y6F8