AGA antibody

Catalog No. ABIN6294189

Product Details anti-AGA Antibody

Target: AGA (Aspartylglucosaminidase (AGA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human AGA

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:1000
IF 1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for AGA

Target: AGA (Aspartylglucosaminidase (AGA))

Alternative Name: AGA (AGA Products)

Synonyms: AGU antibody, ASRG antibody, GA antibody, AW060726 antibody, aspartylglucosaminidase antibody, AGA antibody, Aga antibody

Background: This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing.

Molecular Weight: 37.208 kDa

Gene ID: 175

UniProt: P20933