VWF antibody (AA 1815-1939)

Catalog No. ABIN6294346

This Rabbit Polyclonal antibody specifically detects VWF in IHC. It exhibits reactivity toward Human.

Quick Overview for VWF antibody (AA 1815-1939) (ABIN6294346)

Target: VWF (Von Willebrand Factor (VWF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VWF antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-VWF Antibody

Binding Specificity: AA 1815-1939

Purpose: Rabbit anti-Human Recombinant von Willebrand Factor / vWFAntibody [IHC only]

Specificity: Cytoplasmic

Purification: Amino acids 1815-1939 from the human protein were used as the immunogen for this recombinant vWF antibody.

Immunogen: Amino acids 1815-1939 from the human protein were used as the immunogen for this recombinant vWF antibody.

Application Details

Application Notes: Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: von Willebrand factor ]

Background:

Target Description: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Gene Symbol: VWF///F8VWF

Gene ID: 7450

UniProt: P04275