VWF antibody (AA 1815-1939)

Catalog No. ABIN6294348

This anti-VWF antibody is a Mouse Monoclonal antibody detecting VWF in WB, IHC, IP, FACS and IF. Suitable for Human.

Quick Overview for VWF antibody (AA 1815-1939) (ABIN6294348)

Target: VWF (Von Willebrand Factor (VWF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VWF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-VWF Antibody

Binding Specificity: AA 1815-1939

Purpose: Mouse anti-Human von Willebrand Factor / vWF Antibody [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: Amino acids 1815-1939 from the human protein were used as the immunogen for this vWF antibody.

Immunogen: Amino acids 1815-1939 from the human protein were used as the immunogen for this vWF antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT
WB: 0.5-1 μg/mL
IP: 1-2 μg/500 μg lysate

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: von Willebrand factor ]

Background:

Target Description: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Gene Symbol: VWF///F8VWF

Gene ID: 7450

UniProt: P04275