Myogenic Differentiation 1 (MYOD1) antibody

Details for Product No. ABIN6297598
Antigen
  • MyoD
  • XMyoD
  • XtmyoD
  • mf25
  • myf3
  • pum
  • MYOD1
  • MYOD
  • myod1
  • myod
  • MYF3
  • PUM
  • bHLHc1
  • AI503393
  • Myod-1
  • MUF3
  • etID309723.25
  • wu:fb57a01
  • zgc:136744
  • myogenic differentiation 1
  • MYOD protein
  • myogenic factor MyoD1
  • myod1
  • MYOD1
  • myod
  • Myod1
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus)
310
175
162
65
3
Host
Mouse
173
144
2
Clonality
Monoclonal
Conjugate
Un-conjugated
14
7
7
7
7
7
7
7
5
5
5
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (IHC)
152
120
91
86
63
63
53
33
22
17
14
13
11
6
4
2
2
2
1
1
Options
Purpose Mouse anti-Human/Mouse/Rat/Chicken MyoD1 Antibody [IHC only]
Immunogen Recombinant mouse MyoD1 protein was used as the immunogen for this MyoD1 antibody.
Specificity Nuclear. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
Purification Recombinant mouse MyoD1 protein was used as the immunogen for this MyoD1 antibody.
Antigen
Alternative Name Myoblast determination protein 1 (MYOD1 Antibody Abstract)
Background

Target Description: Recognizes a phosphor-protein of 45 kDa, identified as MyoD1. The epitope of this mAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.

Gene Symbol: MYOD1///BHLHC1///MYF3///MYOD

Gene ID 4654
UniProt P15172
Pathways Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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