Tyrosinase-Related Protein 1 antibody (TYRP1)

Details for Product anti-TYRP1 Antibody No. ABIN6297639
Antigen
  • CAS2
  • CATB
  • GP75
  • OCA3
  • TRP
  • TRP1
  • TYRP
  • b-PROTEIN
  • hm:zeh0659
  • tyrp1
  • zgc:100893
  • B
  • TYRP1
  • tyrp-1
  • TRP-1
  • Tyrp
  • b
  • brown
  • isa
  • tyrosinase related protein 1
  • tyrosinase-related protein 1b
  • tyrosinase-related protein 1
  • tyrosinase-related protein 1 L homeolog
  • tyrosinase-related protein 1a
  • TYRP1
  • tyrp1b
  • Tyrp1
  • tyrp1.L
  • tyrp1
  • LOC100136490
  • tyrp-1
  • tyrp1a
Reactivity
Human, Mouse (Murine)
228
132
12
8
7
5
5
5
5
5
4
3
3
3
2
2
2
Host
Mouse
122
120
Clonality
Monoclonal
Conjugate
This Tyrosinase-Related Protein 1 antibody is un-conjugated
12
8
6
6
6
6
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
120
119
90
68
55
47
34
22
21
16
14
3
2
Options
Purpose Mouse anti-Human/Mouse TRP-1 Antibody Cocktail [Sodium Azide Free]
Immunogen SK-MEL-23 cells (TA99) and recombinant full-length human protein (TYRP1/807) were used as the immunogen for the TRP-1 antibody cocktail.
Specificity Cytoplasmic
Purification SK-MEL-23 cells (TA99) and recombinant full-length human protein (TYRP1/807) were used as the immunogen for the TRP-1 antibody cocktail.
Plasmids, Primers & others Plasmids, Primers & others Tyrosinase-Related Protein 1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name 5,6-dihydroxyindole-2-carboxylic acid oxidase (TYRP1 Antibody Abstract)
Background

Target Description: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Gene Symbol: TYRP1///CAS2///TYRP///TYRRP

Gene ID 7306
UniProt P17643
Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (Frozen Only): 0.5-1 μg/mL for 30 min at RT
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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