s100b antibody (S100 Calcium Binding Protein B)

Details for Product anti-S100B Antibody No. ABIN6297884
Antigen
  • NEF
  • S100
  • S100-B
  • S100beta
  • S100P
  • AI850290
  • Bpb
  • si:dkey-110p14.2
  • wu:fq18b10
  • zgc:92776
  • S100 calcium binding protein B
  • S100 protein, beta polypeptide, neural
  • S100 calcium binding protein, beta (neural)
  • S100B
  • S100b
  • s100b
Reactivity
Human, Mouse (Murine)
375
248
221
171
40
25
8
7
4
2
2
1
1
1
Host
Rabbit
213
203
11
4
3
1
Clonality
Polyclonal
Conjugate
This s100b antibody is un-conjugated
38
27
14
9
9
9
5
5
5
5
5
5
5
5
5
5
5
5
5
5
4
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
351
190
163
161
115
63
60
28
25
22
16
14
9
7
4
3
2
2
1
1
1
Options
Purpose Rabbit Anti-S100B Antibody
Immunogen This S100B antibody is generated from rabbits immunized with S100B recombinant protein.
Plasmids, Primers & others Plasmids, Primers & others s100b products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name S100B (S100B Antibody Abstract)
Background

Target Description: S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Gene Symbol: S100B

Gene ID 6285
UniProt P04271
Pathways Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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