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MCM7 antibody (N-Term)

MCM7 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630182
  • Target See all MCM7 Antibodies
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Binding Specificity
    • 28
    • 15
    • 13
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 118
    • 30
    • 23
    • 11
    • 10
    • 9
    • 9
    • 9
    • 4
    • 2
    • 1
    Human
    Host
    • 81
    • 36
    • 2
    Rabbit
    Clonality
    • 77
    • 42
    Polyclonal
    Conjugate
    • 72
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM7 antibody is un-conjugated
    Application
    • 79
    • 35
    • 32
    • 24
    • 22
    • 20
    • 13
    • 13
    • 12
    • 11
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    MCM7 antibody was raised against the N terminal of MCM7
    Purification
    Purified
    Immunogen
    MCM7 antibody was raised using the N terminal of MCM7 corresponding to a region with amino acids MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYV
    Top Product
    Discover our top product MCM7 Primary Antibody
  • Application Notes
    WB: 2.5 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    MCM7 Blocking Peptide, catalog no. 33R-5687, is also available for use as a blocking control in assays to test for specificity of this MCM7 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM7 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Alternative Name
    MCM7 (MCM7 Products)
    Synonyms
    CDC47 antibody, MCM2 antibody, P1.1-MCM3 antibody, P1CDC47 antibody, P85MCM antibody, PNAS146 antibody, MCM7 antibody, AI747533 antibody, Mcmd7 antibody, mCDC47 antibody, chunp6911 antibody, nyz175 antibody, sr:nyz175 antibody, cdc47 antibody, cdc47-2 antibody, mcm7 antibody, xmcm7 antibody, CG4978 antibody, DmMCM7 antibody, DmeMCM7 antibody, Dmel\\CG4978 antibody, McM7 antibody, Mcp-PCR1 antibody, PCR1 antibody, anon-EST:Liang-1.66 antibody, clone 1.66 antibody, minichromosome maintenance complex component 7 antibody, mini-chromosome maintenance complex protein 7 antibody, minichromosome maintenance complex component 2 antibody, minichromosome maintenance complex component 7 L homeolog antibody, Minichromosome maintenance 7 antibody, minichromosome maintenance complex component 7 S homeolog antibody, MCM complex subunit Mcm7 antibody, MCM7 antibody, CDC47 antibody, Mcm7 antibody, MCM2 antibody, mcm7 antibody, mcm7.L antibody, mcm7.S antibody
    Background
    MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB.
    Molecular Weight
    42 kDa (MW of target protein)
    Pathways
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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