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NR0B2 antibody (N-Term)

NR0B2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630500
  • Target See all NR0B2 Antibodies
    NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
    Binding Specificity
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 49
    • 17
    • 16
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 42
    • 9
    Rabbit
    Clonality
    • 45
    • 6
    Polyclonal
    Conjugate
    • 36
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR0B2 antibody is un-conjugated
    Application
    • 35
    • 17
    • 16
    • 15
    • 11
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    NR0 B2 antibody was raised against the N terminal of NR0 2
    Purification
    Affinity purified
    Immunogen
    NR0 B2 antibody was raised using the N terminal of NR0 2 corresponding to a region with amino acids STSQPGACPCQGAASRPAILYALLSSSLKAVPRPRSRCLCRQHRPVQLCA
    Top Product
    Discover our top product NR0B2 Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    NR0B2 Blocking Peptide, catalog no. 33R-8889, is also available for use as a blocking control in assays to test for specificity of this NR0B2 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NR0 2 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
    Alternative Name
    NR0B2 (NR0B2 Products)
    Synonyms
    SHP antibody, SHP1 antibody, SHP-1 antibody, Shp1 antibody, Shp antibody, NR0B2-A antibody, Nr0b2 antibody, SHP-A antibody, gb:bc058069 antibody, nuclear receptor subfamily 0 group B member 2 antibody, nuclear receptor subfamily 0, group B, member 2 antibody, nuclear receptor subfamily 0, group B, member 2a antibody, NR0B2 antibody, Nr0b2 antibody, nr0b2a antibody
    Background
    NR0B2 is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. It is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function.
    Molecular Weight
    28 kDa (MW of target protein)
    Pathways
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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