NR0B1 antibody (N-Term)
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- Target See all NR0B1 Antibodies
- NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR0B1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- NR0 B1 antibody was raised against the N terminal of NR0 1
- Purification
- Affinity purified
- Immunogen
- NR0 B1 antibody was raised using the N terminal of NR0 1 corresponding to a region with amino acids MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVG
- Top Product
- Discover our top product NR0B1 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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NR0B1 Blocking Peptide, catalog no. 33R-5660, is also available for use as a blocking control in assays to test for specificity of this NR0B1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NR0 1 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
- Alternative Name
- NR0B1 (NR0B1 Products)
- Synonyms
- DAX antibody, NR0B1 antibody, dax1 antibody, AHC antibody, AHCH antibody, AHX antibody, DAX-1 antibody, DAX1 antibody, DSS antibody, GTD antibody, HHG antibody, NROB1 antibody, SRXY2 antibody, Ahc antibody, Ahch antibody, Dax1 antibody, nuclear receptor subfamily 0 group B member 1 antibody, nuclear receptor subfamily 0, group B, member 1 antibody, nuclear receptor subfamily 0 group B member 1 L homeolog antibody, NR0B1 antibody, nr0b1 antibody, nr0b1.L antibody, Nr0b1 antibody
- Background
- NR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
- Molecular Weight
- 52 kDa (MW of target protein)
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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