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ABAT antibody (Middle Region)

ABAT Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630787
  • Target See all ABAT Antibodies
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    Binding Specificity
    • 15
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 40
    • 26
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 36
    • 5
    Rabbit
    Clonality
    • 35
    • 6
    Polyclonal
    Conjugate
    • 27
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABAT antibody is un-conjugated
    Application
    • 40
    • 15
    • 13
    • 13
    • 10
    • 8
    • 5
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Specificity
    ABAT antibody was raised against the middle region of ABAT
    Purification
    Affinity purified
    Immunogen
    ABAT antibody was raised using the middle region of ABAT corresponding to a region with amino acids IIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFW
    Top Product
    Discover our top product ABAT Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    ABAT Blocking Peptide, catalog no. 33R-4009, is also available for use as a blocking control in assays to test for specificity of this ABAT antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ABAT antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    Alternative Name
    ABAT (ABAT Products)
    Synonyms
    cb880 antibody, fj82a01 antibody, wu:fj82a01 antibody, BA0325 antibody, PSPTO0259 antibody, PSPTO0301 antibody, PSPTO1890 antibody, GABA-AT antibody, GABAT antibody, NPD009 antibody, GABA-T antibody, L-AIBAT antibody, 9630038C02Rik antibody, AI255750 antibody, ENSMUSG00000051226 antibody, Gabaat antibody, Gabat antibody, Gm9851 antibody, I54 antibody, Laibat antibody, X61497 antibody, beta-AlaAT antibody, 4-aminobutyrate aminotransferase antibody, 4-aminobutyrate--2-oxoglutarate transaminase antibody, GABA aminotransferase PLP-dependent PuuE antibody, 4-aminobutyrate aminotransferase, mitochondrial antibody, aspartate aminotransferase family protein antibody, 4-aminobutyrate aminotransferase S homeolog antibody, ABAT antibody, abat antibody, gabT antibody, puuE antibody, gabT-1 antibody, gabT-2 antibody, gabT-3 antibody, CNE01830 antibody, Mmwyl1_0047 antibody, CpipJ_CPIJ008729 antibody, KCR_RS04555 antibody, Bcenmc03_4909 antibody, Hden_0972 antibody, Dbac_2000 antibody, Mesil_2400 antibody, Trad_0121 antibody, abat.S antibody, Abat antibody
    Background
    4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50 kDa subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde
    Molecular Weight
    55 kDa (MW of target protein)
    Pathways
    Monocarboxylic Acid Catabolic Process
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