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TNNT1 antibody

TNNT1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN631158
  • Target See all TNNT1 Antibodies
    TNNT1 (Slow Skeletal Troponin T (TNNT1))
    Reactivity
    • 27
    • 14
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 25
    • 6
    • 1
    Rabbit
    Clonality
    • 28
    • 4
    Polyclonal
    Conjugate
    • 20
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNNT1 antibody is un-conjugated
    Application
    • 25
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purified
    Immunogen
    Troponin T Type 1 antibody was raised using a synthetic peptide corresponding to a region with amino acids WIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK
    Top Product
    Discover our top product TNNT1 Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    Troponin T Type 1 Blocking Peptide, catalog no. 33R-9957, is also available for use as a blocking control in assays to test for specificity of this Troponin T Type 1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TNNT1 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    TNNT1 (Slow Skeletal Troponin T (TNNT1))
    Abstract
    TNNT1 Products
    Synonyms
    ANM antibody, NEM5 antibody, STNT antibody, TNT antibody, TNTS antibody, TNNI1 antibody, AW146156 antibody, Tnt antibody, sTnT antibody, ssTnT antibody, Fang2 antibody, tnTs antibody, Tnnt antibody, zgc:193831 antibody, zgc:193865 antibody, troponin T1, slow skeletal type antibody, troponin I1, slow skeletal type antibody, troponin T1, skeletal, slow antibody, troponin T1, slow skeletal type S homeolog antibody, troponin T type 1 (skeletal, slow) antibody, TNNT1 antibody, TNNI1 antibody, Tnnt1 antibody, tnnt1.S antibody, tnnt1 antibody
    Background
    TNNT1 is a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year.
    Molecular Weight
    33 kDa (MW of target protein)
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