TNNT1 antibody
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- Target See all TNNT1 Antibodies
- TNNT1 (Slow Skeletal Troponin T (TNNT1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNNT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purified
- Immunogen
- Troponin T Type 1 antibody was raised using a synthetic peptide corresponding to a region with amino acids WIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK
- Top Product
- Discover our top product TNNT1 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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Troponin T Type 1 Blocking Peptide, catalog no. 33R-9957, is also available for use as a blocking control in assays to test for specificity of this Troponin T Type 1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TNNT1 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- TNNT1 (Slow Skeletal Troponin T (TNNT1))
- Abstract
- TNNT1 Products
- Synonyms
- ANM antibody, NEM5 antibody, STNT antibody, TNT antibody, TNTS antibody, TNNI1 antibody, AW146156 antibody, Tnt antibody, sTnT antibody, ssTnT antibody, Fang2 antibody, tnTs antibody, Tnnt antibody, zgc:193831 antibody, zgc:193865 antibody, troponin T1, slow skeletal type antibody, troponin I1, slow skeletal type antibody, troponin T1, skeletal, slow antibody, troponin T1, slow skeletal type S homeolog antibody, troponin T type 1 (skeletal, slow) antibody, TNNT1 antibody, TNNI1 antibody, Tnnt1 antibody, tnnt1.S antibody, tnnt1 antibody
- Background
- TNNT1 is a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year.
- Molecular Weight
- 33 kDa (MW of target protein)
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