TREM2 antibody (Middle Region)

Catalog No. ABIN633058

Product Details anti-TREM2 Antibody

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TREM2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: TREM2 antibody was raised against the middle region of TREM2

Purification: Affinity purified

Immunogen: TREM2 antibody was raised using the middle region of TREM2 corresponding to a region with amino acids FPGESESFEDAHVEHSISRSLLEGEIPFPPTSILLLLACIFLIKILAASA

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TREM2 Blocking Peptide, catalog no. 33R-3016, is also available for use as a blocking control in assays to test for specificity of this TREM2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TREM2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: TREM2 (TREM2 Products)

Synonyms: TREM-A1 antibody, TREM-B1 antibody, TREM2 antibody, trem-2 antibody, trem2a antibody, trem2b antibody, trem2c antibody, TREM-2 antibody, Trem2a antibody, Trem2b antibody, Trem2c antibody, triggering receptor expressed on myeloid cells 2 antibody, trem-like transcript 2 protein antibody, TREM2 antibody, trem2 antibody, LOC100228399 antibody, Trem2 antibody

Background: The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).

Molecular Weight: 25 kDa (MW of target protein)