HSD3B7 antibody (Middle Region)
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- Target See all HSD3B7 Antibodies
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HSD3B7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- HSD3 B7 antibody was raised against the middle region of HSD3 7
- Purification
- Affinity purified
- Immunogen
- HSD3 B7 antibody was raised using the middle region of HSD3 7 corresponding to a region with amino acids QGTRNVIEACVQTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHR
- Top Product
- Discover our top product HSD3B7 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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HSD3B7 Blocking Peptide, catalog no. 33R-7574, is also available for use as a blocking control in assays to test for specificity of this HSD3B7 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HSD0 7 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
- Alternative Name
- HSD3B7 (HSD3B7 Products)
- Synonyms
- CBAS1 antibody, PFIC4 antibody, SDR11E3 antibody, AI195443 antibody, BB098564 antibody, Cca2 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 antibody, HSD3B7 antibody, Hsd3b7 antibody
- Background
- This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 41 kDa (MW of target protein)
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