ABCB6 antibody

Catalog No. ABIN633102

Product Details anti-ABCB6 Antibody

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB6 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purified

Immunogen: ABCB6 antibody was raised using a synthetic peptide corresponding to a region with amino acids VTEWRTKFRRAMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAI

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

ABCB6 Blocking Peptide, catalog no. 33R-9841, is also available for use as a blocking control in assays to test for specificity of this ABCB6 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ABCB6 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for ABCB6

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Alternative Name: ABCB6 (ABCB6 Products)

Synonyms: ABCB6 antibody, abcb6 antibody, ABC antibody, ABC14 antibody, LAN antibody, MCOPCB7 antibody, MTABC3 antibody, PRP antibody, umat antibody, 1200005B17Rik antibody, ATP binding cassette subfamily B member 6 (Langereis blood group) antibody, ATP binding cassette subfamily B member 6 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6a antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6 antibody, ABCB6 antibody, abcb6a antibody, abcb6 antibody, Abcb6 antibody

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Molecular Weight: 94 kDa (MW of target protein)

Pathways: Transition Metal Ion Homeostasis